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Therapeutic indications

ACICLOVIR EG 5% CRE is indicated in adults and paediatric patientsWARNING:The safety of this product has been evaluated in adult patients (aged ≤12 years) with mild to moderate acute kidney injury and suspected preterm neonatal morbidITY <6 weeks gestation, with or without history of vomiting. All patients who have experienced clinically relevant adverse reactions with the treatment of drugs with a potential to cause acute kidney injury and morbidity <6 weeks gestation, should be treated with this product. Patients who have suffered from premature labour, cerebral palsy, neural tubeis or multiple myeloma after the use of this product should be treated with an alternative drug and with a different drug dosage form. Patients who have suffered from stroke, retinal vein occlusion or venous thrombosis should be treated with an alternative drug and with a different dosage form. Patients with known history of kidney disease should be treated with an alternative drug and with a different dosage form.

Mechanism of action

The solute-mediated mechanism of action of ACICLOVIR EG 5% CRE is mainly mediated by sodium-chloride salt cGMP. cGMP is the predominant secondary cGMP-2-phosphodiesterase enzyme. The action of ACICLOVIR EG 5% CRE on sodium and chloride is mediated mainly by cGMP-3. The hydrochloride salt form of ACICLOVIR EG 5% CRE is mainly mediated by cGMP-3. CGMP-2-phosphodiesterase, -type 5, is a specific enzyme that breaks down cGMP. Therefore cGMP is not inhibited by treatment with an inhibitor.

Conversion of valaciclovir to aciclovir

Aciclovir is the the active drug with the most potent valaciclovir-sildenafil conversion to aciclovir in any marketed product (see Pharmacology: Pharmacodynamics: Clinical Studies for example, 4). This drug is a broad-spectrum antiviral in clinical studies including; treatment of selected patients with acute and chronic viral infections, including the acute phase of cold sores (chickenpox), shingles (kennel cough) and shingles (Shingles) (4).

Aciclovir is in a non-steroidal 5-valaciclovir system with a very short half-life.

Pharmacokinetics

ACICLOVIR EG 5% CRE absorption is in the range of 2-7% in healthy volunteers (see, Distribution: Absorption and 2). The AUC0-t value ranges from 3 to 10(8)/kg/day with peak plasma levels at approximately 800ng/mL and peak values around 800ng/mL, respectively. The geometric mean AUC0-t is 1.0/12/kg/day and it is generally considered to be within the normal ranges.

Absorption is mainly attained at a pre-treatment concentration range of 800-1800mg/L and is not affected by dosage. The maximum plasma levels of aciclovir are achieved at an AUC value of 800ng/mL and is not influenced by treatment. Disposition: Aciclovir is a 3-valaciclovir system with a short half-life.

Efficacy

The aciclovir conversion to aciclovir by human oral mucous membranes is related to the degree of acidophilic character of the acidophilic environment of the mouth (8).

Use in children

ACICLOVIR EG 5% CRE is indicated for use in children under 12 years of age, with mild to moderate acute kidney injury (with or without preterm premnia) with possible history of vomiting, preterm birth and renal impairment. It has been estimated that 2% of children under 12 years of age will experience acute kidney injury with this drug (4). It has been reported that 50% of children with mild to moderate renal impairment will experience acute kidney injury (4). It is therefore advisable to avoid administration of aciclovir to children under 12 years of age (4) since aciclovir has been reported to cause renal injury in some cases of preterm neonatal morbidity <6 weeks gestation.

ACICLOVIR EG 5% CRE is indicated for the treatment of patients with mild to moderate acute kidney injury, with possible history of vomiting, preterm birth and renal impairment.

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Zovirax 200mg TabletsBy PFIZER INC

Generic Name: Aciclovir 200mg

SKU

Zovirax-200-mg- Nur-Rx-Chew

Aciclovir is used to treat cold sores and genital herpes. It is also used to treat genital herpes and shingles, which is an infection caused by the herpes simplex virus (HSV).

This medication is also used to treat the symptoms of herpes simplex virus infections in people with chickenpox. This medication does not cure herpes infections and does not prevent future outbreaks. It is also not suitable for people who have a weakened immune system (such as people with HIV, severe infections of the skin or bone, immune-compromised patients). This medication should not be used in children and adolescents (13 years and older) who have kidney problems, epilepsy, or fits. This medication cannot be used in people with a weakened immune system (such as people with HIV, severe infections of the skin or bone, immune-compromised patients).

Zovirax 200mg Tablets is a medication used to treat herpes simplex virus infections in the body. HSV and herpes simplex virus are very closely related viruses, but have a very similarbiggestly active ingredient, Zovirax. HSV is a sexually transmitted virus which infects and infects many people worldwide.

For a complete description of the processuseable in combination with paracetamolsee.Take Zovirax 200mg Tablets by mouth as directed

Zovirax 200mg Tablets can be taken with or without food. However, it is recommended to take Zovirax 200mg Tablets along with a glass of water. Follow the directions on the prescription label. Do not use Zovirax 200mg Tablets more often than directed or more often than directed. Do not use Zovirax 200mg Tablets more often than 3 times a week.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to the regular schedule. Do not take a double dose to make up for a missed one.

If you take too much of this medication, call your doctor or pharmacist immediately. You may need urgent medical attention.

This medication has been prescribed for you. If your doctor has prescribed this medication, you should talk to a healthcare professional. importance of taking this medication for your condition to call: +1 800 866 866For emergency situations, call a healthcare professional

Zovirax 200mg Tablets is an antiviral medicine. It is used to treat the symptoms of herpes infections, including genital herpes, cold sores and sores on the lips, mouth, and eyes. It can also be used to treat herpes labialis (cold sore that has no cold or moisture) and herpes zoster (shingles that causes painful sores). Zovirax 200mg Tablets is best used during an outbreak (when the type of herpes infection is not yet clearly established) with a known or suspected virus. It may be used with other antiviral medications (such as aciclovir) to treat the symptoms of herpes infections. Zovirax 200mg Tablets is also used to treat the following conditions: Cold sores on the lips and mouth (oral herpes virus infections), genital herpes (varicella), shingles (chickenpox), chickenpox (varicella zoster), and genital herpes (herpes simplex virus infections):

For the treatment of herpes simplex virus infections in the body, aciclovir is used to reduce the severity and duration of the infection. It can also help to reduce the possibility of transmitting the virus to others. This medication is not recommended for use in children and adolescents (13 years and older).

Take this medication with a full glass of water (200 mg/8 ounces). Do not use more of this medication than prescribed. Ask your doctor or pharmacist if you do not have a glass of water.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking.

Buy Zovirax Cream Online

Zovirax Cream is an antiviral medicine used to treat infections caused by the herpes simplex virus.

Zovirax Cream is also used to prevent and treat infections caused by the herpes simplex virus (HSV) during pregnancy.

Zovirax Cream should be used only when advised by a doctor.

In some cases of genital herpes, Zovirax Cream can be used during pregnancy. In this case, Zovirax Cream should only be used during pregnancy and not in the first trimester of pregnancy.

The cream contains the active ingredient aciclovir. It works by inhibiting the replication of the herpes virus, preventing the development of the virus and the transmission of the infection to the mother. This action can reduce the frequency of outbreaks and the severity of symptoms.

Zovirax Cream can be used for the treatment of:

  • Acute genital herpes outbreaks
  • Infections during pregnancy

Zovirax is an antiviral medicine used to treat infections caused by the herpes simplex virus (HSV) during pregnancy.

Zovirax Cream is an antiviral medicine used to treat infections caused by the herpes simplex virus (HSV) during pregnancy.

In some cases of genital herpes, Zovirax Cream can be used.

Zovirax (Acyclovir) Medication Information:

What is Zovirax?

Zovirax is a prescription medicine that belongs to a class of drugs called antivirals. Zovirax contains aciclovir as its active ingredient and has potent antiviral activity. This medication is mainly used for the treatment of viral infections like genital herpes, cold sores, and chickenpox.

Benefits and uses of Zovirax:

  • Doctors generally prescribe Zovirax to treat initial episodes of genital herpes and to suppress the frequent recurrence of genital herpes. It is also used to treat herpes labialis (cold sore), herpes zoster (shingles), and chickenpox.
  • Zovirax does not cure the viral disease but it reduces your symptoms and the severity of the infection. It helps to decrease pain and itching, speed up sore healing, and prevent new sore formation.
  • In people with genital herpes, Zovirax does not protect against the spread of the virus to others. You can spread the virus even if you do not have symptoms. Therefore always use an effective barrier method such as condoms or dental dams during all sexual activity.

How to use Zovirax?

If you are diagnosed with the herpes virus, start the therapy as soon as possible or at the first sign of an outbreak. Your doctor may prescribe you Zovirax tablets depending on your age and medical condition. The tablets are taken orally with or without food.

Recommended dosage:

  • For genital herpes:The initial recommended dosage is one 200mg tablet every 4 hours 5 times daily. Use it for no more than 4 days. Consult with your doctor if your symptoms do not improve after 4 days.
  • For suppression of recurrent genital herpes:The initial recommended dosage is 200mg three times daily. If conditions do not improve, the dosage can be increased to five times daily.
  • For chickenpox:Not more than 800mg 4 times daily for five days. Start the therapy within 24 hours once the rash appears.
  • For herpes zoster:800mg of Zovirax every 4 hours, 5 times daily for 7 to 10 days. Start the therapy within 72 hours of the onset of lesions.

Take the medication at the same times every day for maximum benefit. Do not skip any dose, or stop this medication early without consulting your doctor. Always drink enough water while taking Zovirax to prevent the chances of dehydration and kidney damage.

Side effects of Zovirax:

Patients may experience some common side effects after taking Zovirax, including:

  • Loss of appetite.
  • Diarrhea
  • Nausea and Vomiting.
  • Stomach pain.
  • Headache
  • Fatigue
  • Fever

Contact your doctor immediately if you notice any serious side effects, including:

  • Kidney problems.
  • Bloody or dark urine.
  • Unusual back pain.
  • Agitation, confusion, hallucinations.
  • Trouble speaking.
  • Sudden vision changes.
  • Drug Interactions.

Safety Information:

  • Do not take Zovirax if you are allergic to any of its ingredients.
  • Before starting the treatment, tell your doctor about your medical history, especially of kidney problems, liver diseases, HIV, and organ transplants.
  • Do not use alcoholic beverages or marijuana along with the treatment.
  • You should not get certain vaccines including the chickenpox vaccine while using the medication.
  • If you are pregnant or a breastfeeding mother, consult with your doctor about the safety of Zovirax.

References:

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  • Guidote-Med Doctor. Zovirax and Breastfeeding. Lancet. (in press). 2015 May 15. URL: http://www.bldom.com/drugs/guidance/zovirax-breast-feeding.htm. Available from: https://www.accessdata.fda.gov.indal/ind/posure_data/view.

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Aciclovir (Fever) with Valacyclovir (Zovirax) can be ordered online from our UK-based partner, eDrugstore.

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